Asymptotic Stability of Stationary Solutions of a Free Boundary Problem Modeling the Growth of Tumors with Fluid Tissues

نویسندگان

  • Junde Wu
  • Shangbin Cui
چکیده

This paper aims at proving asymptotic stability of the radial stationary solution of a free boundary problem modeling the growth of nonnecrotic tumors with fluid-like tissues. In a previous paper we considered the case where the nutrient concentration σ satisfies the stationary diffusion equation ∆σ = f(σ), and proved that there exists a threshold value γ∗ > 0 for the surface tension coefficient γ, such that the radial stationary solution is asymptotically stable in case γ > γ∗, while unstable in case γ < γ∗. In this paper we extend this result to the case where σ satisfies the non-stationary diffusion equation ε∂tσ = ∆σ−f(σ). We prove that for the same threshold value γ∗ as above, for every γ > γ∗ there is a corresponding constant ε0(γ) > 0 such that for any 0 < ε < ε0(γ) the radial stationary solution is asymptotically stable with respect to small enough non-radial perturbations, while for 0 < γ < γ∗ and ε sufficiently small it is unstable under non-radial perturbations. AMS subject classification: 35R35, 35B35, 76D27.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Asymptotic Behavior of Solutions of a Free Boundary Problem Modelling the Growth of Tumors with Stokes Equations

We study a free boundary problem modelling the growth of non-necrotic tumors with fluid-like tissues. The fluid velocity satisfies Stokes equations with a source determined by the proliferation rate of tumor cells which depends on the concentration of nutrients, subject to a boundary condition with stress tensor effected by surface tension. It is easy to prove that this problem has a unique rad...

متن کامل

On Approximate Stationary Radial Solutions for a Class of Boundary Value Problems Arising in Epitaxial Growth Theory

In this paper, we consider a non-self-adjoint, singular, nonlinear fourth order boundary value problem which arises in the theory of epitaxial growth. It is possible to reduce the fourth order equation to a singular boundary value problem of second order given by w''-1/r w'=w^2/(2r^2 )+1/2 λ r^2. The problem depends on the parameter λ and admits multiple solutions. Therefore, it is difficult to...

متن کامل

A two-phase free boundary problem for a semilinear elliptic equation

In this paper we study a two-phase free boundary problem for a semilinear elliptic equation on a bounded domain $Dsubset mathbb{R}^{n}$ with smooth boundary‎. ‎We give some results on the growth of solutions and characterize the free boundary points in terms of homogeneous harmonic polynomials using a fundamental result of Caffarelli and Friedman regarding the representation of functions whose ...

متن کامل

HALL AND LON-SLIP EFFECTS ON MAGNETO-MICROPOLAR FLUID WITH COMBINED FORCED AND FREE CONVECTION IN BOUNDARY LAYER FLOW OVER A HORIZONTAL PLATE WITH VISCOUS DISSIPATION

In this paper, we study the effects of Hall and ion-slip currents on the steady magneto-micropolar of a viscous incompressible and electrically conducting fluid over a horizontal plate by taking in to account the viscous dissipation effects. By means of similarity solutions, deviation of fundamental equations on the assumption of small magnetic Reynolds number are solved numerically by using qu...

متن کامل

Concerning the Effect of a Viscoelastic Foundation on the Dynamic Stability of a Pipeline System Conveying an Incompressible Fluid

In this paper, we present an analytical method for solving a well-posed boundary value problem of mathematical physics governing the vibration characteristics of an internal flow propelled fluid-structure interaction where the pipeline segment is idealized as an elastic hollow beam conveying an incompressible fluid on a viscoelastic foundation. The effect of Coriolis and damping forces on the o...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • SIAM J. Math. Analysis

دوره 41  شماره 

صفحات  -

تاریخ انتشار 2009